Methamphetamine has a high potential for abuse. Methamphetamine has effects similar to amphetamine, although CNS effects are more pronounced and peripheral ones are less prominent. The acute toxic effects of amphetamine (tremor, irritability, insomnia, confusion, anxiety, delirium, and hallucinations) are extension of the pharmacological effects and may be due to an increased release of serotonin from nerve terminals, or to direct effects on serotoninergic neurons. Most of amphetamine's effects are believed to be due to its ability to stimulate the release of biogenic amines (norepinephrine and dopamine) from their storage sites in the nerve terminals. Main effects of acute administration are wakefulness, decreased sense of fatigue, elevation of mood, and increased ability to concentrate. ![]() Aschner, in Encyclopedia of the Neurological Sciences (Second Edition), 2014 AbstractĪmphetamine has powerful central nervous system (CNS) stimulant actions, in addition to peripheral actions typical of indirect sympathomimetic drugs.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |